Spreads signal on interaction network to identify altered subnetworks.


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Documentation for package ‘BioNetSmooth’ version 1.0.0

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construct_network Builds a graph using a list of interacting genes or proteins
construct_weighted_network Builds an edge weighted graph using a list of interacting genes or proteins
expr_mat Input matrix for smoothing
network dataframe of interacting proteins of C.elegans from STRING database
network_bias_correction Network propagated scores are corrected by subtracted with mean inital propagated scores.
network_mapping Maps initial expression scores to an interaction network
network_mapping_weighted Maps initial expression scores to an edge weighted interaction network
network_smoothing function for identifing active genes and their neighbours through propagating expression scores on an interaction network
propagate_algebra propagates node scores on a graph